Combine the ground beef, Italian sausage, and onion in a large, deep sauce pan or Dutch oven. Cook over medium high heat, breaking apart the meat with a spatula, until no pink remains. Drain any excess fat off the pan, then stir in garlic, pasta sauce, oregano, and salt, and pepper, to taste. Heat through, then reduce heat to low. Allow the sauce to simmer while you prepare the rest of the ingredients.